姓  名:郑其平
技术职称:江苏大学 特聘教授





郑其平,1965年11月生,理学博士,江苏大学教授,硕士生导师。

1982-1987年就读于安徽医科大学医疗系,获医学学士学位。1987-1990年于苏州医学院攻读硕士研究生获硕士学位。1990-1995年,于南京市脑科医院神经与精神科从事临床与实验研究工作。1995-1998年在复旦大学遗传所攻读遗传学并获理学博士学位。1999-2004年于美国休斯敦市贝勒医学院的人类与分子遗传学系从事博士后研究。2004-2007年被贝勒医学院人类与分子遗传系聘任为研究助理教授。2007-2012任拉什大学医学中心解剖与细胞生物系助理教授。2012年6月任江苏大学(特聘)教授。



1. Gu J, Li, X., Liang, Y., Qiao, L., Ran, D., Lu, Y., Li, X., Wei, W, and Zheng, Q. (2013). Upregulation of URI/RMP gene expression in cervical cancer by high-throughput tissue microarray analysis. Int J Clin Exp Pathol 2013;6(4):669-677 www.ijcep.com /ISSN:1936-2625 / IJCEP1302019, (Corresponding author).

2. Lu Y, Abassi S, Li F, Ding, M, Wu G, Gu J, and Zheng, Q. (2013). Distinct function of P63 isoforms during embryonic skeletal development. Gene Feb 26; 519(2):251-259 (2013), doi: 10.1016/j.gene.2013.02.021. [Epub ahead of print] (Corresponding author).

3. Ding, M., Lu, Y., Abbassi, S., Sumner, D., Li, F., Song, Y., Geoffroy, V., and Zheng, Q., (2012). Targeting Runx2 expression in hypertrophic chondrocytes impairs endochondral ossification during early skeletal development. J Cell Physiol. 2012 Oct;227(10):3446-56. doi: 10.1002/jcp.24045. (Corresponding author).

4. Li, F., Lu, Y., Ding, M., Wu, G, Sinha, S., Wang, S., and Zheng, Q. (2012). Putative function of TAP63α during endochondral bone formation. Gene Mar 10; 495(2):95-103 (2012), doi:10.1016/j.gene.2011.12.057. (Corresponding author).

5. Li, F., Lu, Y., Ding, M., Napierala, D., Abbassi, S., Chen, Y., Duan, X., Wang, S., Lee, B., and Zheng, Q. (2011). Runx2 contributes to murine Col10a1 gene regulation through direct interaction with its cis-enhancer. J Bone Miner Res. 26(12):2899-2910. (Corresponding author).

6. Yang, H., Gu, J., Zheng, Q., Li, M., Lian, X., Miao, J., Jiang, J., and Wei, W. (2011). RPB5-Mediating Protein (RMP) is required for the proliferation of hepatocellular carcinoma cells. J Biol. Chem. 286(13):11865-74.

7. Li, F; Jiang, Y; Zheng, Q ; Yang, X; and Wang, S. (2011). TEC protein tyrosine kinase is involved in the Erk signaling pathway induced by HGF. Biochem Biophys Res Commun. 404(1):79-85.

8. Gu, J., Sun, D., Zheng, Q., Wang, X., Yang, H., Miao, J., Jiang, J., and Wei, W. (2009). Human Elongator complex is involved in cell cycle and suppresses cell growth in 293 T human embryonic kidney cells. Acta Biochim Biophys Sinica. 41(10):831-8. 

9. Zheng, Q., Keller, B., Zhou, G., Napierala, D., Chen, Y., Zabel, B., Parker, A., and Lee, B (2009). Localization of the cis-enhancer element for mouse type X collagen gene expression in hypertrophic chondrocytes in vivo. J Bone Miner Res. 24(6):1022-1032 (Corresponding author). 

10. Napierala, D., Sam, K., Morello, R., Zheng, Q., Munivez, E., Shivdasani, RA., and Lee, B (2008). Uncoupling of chondrocyte differentiation and perichondrial mineralization underlies the skeletal dysplasia in tricho-rhino-phalangeal syndrome. Hum Mol Genet. 17(14):2244-54. 

11. Zhou, G., Zheng, Q., Engin, F., Munimez, E., Chen, Y., Sebald, E., Krakow, D., and Lee, B. (2006). Dominance of SOX9 function over RUNX2 during skeletogenesis. Proc Natl Acad Sci USA. 103(50):19004-9. 

12. Napierala, D., Garcia-Rojas, X., Sam, K., Wakui, K., Chen, C., Mendoza-Londono, R., Zhou, G., Zheng, Q., and Lee, B. (2005). Mutations and Promoter SNPs in RUNX2, a Transcriptional Regulator of Bone Formation. Mol Genet Metab 86(1-2): 257-68. 

13. Zheng, Q., Sebald, E., Zhou, G., Chen, Y., Wilcox, W., Lee, B., and Krakow, D. (2005). Dysregulation of Chondrogenesis in Human Cleidocranial Dysplasia. Am J Hum Genet 77(2):305-12.

14. Zheng, Q., Zhou, G., Morello, R., Chen, Y., Garcia-Rojas, X., and Lee, B. (2003). Type X Collagen Gene Regulation by RUNX2 Contributes Directly to Its Hypertrophic Chondrocyte-specific Expression In Vivo. J Cell Biol. 162 (5): 833-842. 

15. Scaglia, F., Zheng, Q., O’Brien, W.E., Henry, J., Rosenberger, J., Reed, P., and Lee, B. (2002). An Integrated Approach to the Diagnosis and Prospective Management of Partial Ornithine Transcarbamylase Deficiency. Pediatrics 2002 Jan; 109(1): 150-2. 

16. Zheng, Q., Yu, L., Zhao, Y., Zhang, H., Fu, Q., Mao, N., Hu, P., Geng, Z., and Zhao, S. (2001). Structure Characterization of Human RalGDS Gene, and the Identification of Its Novel Variant Molecular Biology Report 27(4):209-16.



1)课题名称:Determinants of type X collagen gene expression during chondrocyte hypertrophy

资金来源:Arthritis Foundation Postdoctoral Fellowship

项目金额与年限: $105,000,three years (2001-2004)

2)课题名称: Mouse Col10a1 gene regulation and skeletal development

资金来源: NIH/NIDCR (R03), DE16041-02

项目金额与年限: $150,500,two years (2004-2006)

3)课题名称: Identification of transcriptional determinants for mouse Col10a1 expression

资金来源: Arthritis Foundation Arthritis Investigator Award

项目金额与年限: $330,000,four years (2006-2010)

4)课题名称: P63 in bone development and cancer formation

资金来源: Rush Pilot Project

项目金额与年限: $150,000,two years (2008-2010)

5)课题名称: Chondrocyte maturation and osteosarcoma

资金来源: Bear Necessities Pediatrics Cancer Foundation

项目金额与年限: $20,000, one year (2010-2011)

6)课题名称: Osteosarcoma translational research

资金来源: NIH/NCI (R21), 1R21CA161461-01A1

项目金额与年限: $366,053,two years (2012-2014)

7)课题名称: In vivo function of Runx2 on murine osteosarcoma development

资金来源: American Cancer Society-Illinois Division

项目金额与年限: $100,000,one year (2013-2014)

8)课题/经费名称:科研启动研究经费

资金来源:拉什大学医学中心征聘人员启动资金(见拉什大学聘用书)

项目金额与年限: $825,000, Three years (2007-2010)

9)课题名称: 颌面部骨骼疾病十型胶原蛋白基因 的异常调控

资金来源: 国家自然科学基金面上项目

项目金额与年限: 70万/4年 (2013-2016)

10)课题名称:RMP是潜在的宫颈癌生物标志物吗?

资金来源: 国家教育部大学生创新创业训练计划项目

项目金额与年限:2万/1年 (2013-2014)



    




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